ICP-MS Elemental Analysis
What is ICP-MS?
ICP-MS (Inductively Coupled Plasma-Mass Spectrometry) is an elemental analysis technique used to detect elements at very low-concentrations at ppm (parts per million), ppb (parts per billion) or ppt (parts per trillion) levels.
Dalton ICP-MS Elemental Analysis Capabilities
In accordance with the updated ICH Q3D Guideline for Elemental Impurities, Dalton now offers ICP-MS Elemental Analysis testing services.
Drug Products have the potential to contain contaminants or elemental residues that may be harmful to the consumer, even in small quantities. It is the responsibility of the manufacturer and distributor to ensure that any hazardous chemicals including heavy metal or elemental impurities meet the current regulatory guidelines for finished products.
With ICP-MS, we can detect:
- Most elements from Li to U except C, N, O, Cl, Br, I and S
- With an optimal detection range from 0.1 ppm to 1% wt & sample size as small as 0.01 g.
- Parts per trillion (ppt) range for many elements in aqueous solutions
The instrument, an Agilent 7800 ICP-MS quadrupole analyzer, is currently validated and ready for use.
We Develop, Validate and Test; Dalton offers:
- GMP Compliant Services
- Analytical Method Development
- Method Validation
- Release Testing
- In-Process Testing
- Stand-Alone Analytical Testing
Contact us for more information on our ICP-MS services.